PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
December 1, 1969Biochemistry155 citations

Enzymic synthesis of deoxyribonucleic acid. XXXIV. Termination of chain growth by a 2',3'-dideoxyribonucleotide

View Full Paper
MAMaurice R. AtkinsonMDMurray P. DeutscherAKArthur Kornberg

Key Points

  • To investigate the role of a 2',3'-dideoxyribonucleotide in halting DNA chain elongation during enzymatic synthesis.
  • Used enzymatic techniques for DNA synthesis
  • Examined the incorporation of dideoxyribonucleotides
  • Analyzed chain termination effects
  • Demonstrated effective termination of DNA chain growth with 2',3'-dideoxyribonucleotide inclusion
  • Showed significant inhibition of further nucleotide addition in enzymatic reactions

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnzymic synthesis of deoxyribonucleic acid. XXXIV. Termination of chain growth by a 2',3'-dideoxyribonucleotideMaurice R. Atkinson, Murray P. Deutscher, Arthur Kornberg, Alan F. Russell, and J. G. MoffattCite this: Biochemistry 1969, 8, 12, 4897–4904Publication Date (Print):December 1, 1969Publication History Published online1 May 2002Published inissue 1 December 1969https://pubs.acs.org/doi/10.1021/bi00840a037https://doi.org/10.1021/bi00840a037research-articleACS PublicationsRequest reuse permissionsArticle Views383Altmetric-Citations120LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Atkinson et al. (1969) studied this question.

synapsesocial.com/papers/6a0cca9d291fe4aa6262551bhttps://doi.org/10.1021/bi00840a037
Ask AI
Helpful
Bookmark
Share
View Full Paper