Key result
Freehand aortic valve replacement using an antibiotic-treated homograft resulted in a 69% six-year survival rate, with important valve incompetence occurring in 9% of patients at six years.
Why the study?
Does freehand aortic valve replacement using an antibiotic sterilized homograft valve provide acceptable long-term survival and valve competence in patients with aortic valve disease?
Population
121 patients operated upon for aortic valve disease
Design
Cohort
Follow-up
four to six and one-half years
Authors
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Supports homograft AVR in aortic disease; leaves open durability questions in dilated aortas pending randomized data.
Observational (n=121)
Does freehand aortic valve replacement using an antibiotic sterilized homograft valve provide acceptable long-term survival and valve competence in patients with aortic valve disease?
Freehand aortic valve replacement with an antibiotic sterilized homograft valve demonstrates acceptable 6-year survival, though valve incompetence is significantly higher in patients with a dilated proximal aorta.
Barratt‐Boyes et al. (1977) conducted an observational in aortic valve disease (n=121). Antibiotic-treated homograft aortic valve inserted in a freehand fashion was evaluated on Six year survival. Freehand aortic valve replacement using an antibiotic-treated homograft resulted in a 69% six-year survival rate, with important valve incompetence occurring in 9% of patients at six years.
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