Key result
Type I persistent common atrioventricular canal was associated with high rates of other cardiac (90%) and noncardiac (80%) malformations, whereas Type II had more Down's syndrome (40%).
Population
35 hearts (specimens) with the complete form of persistent common atrioventricular canal.
Design
Case_series
Authors
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Findings from this case report should not change practice; leaves open questions on embryological timing and targeted screening in atrioventricular canal defects.
Observational (n=35)
Type I persistent common atrioventricular canals are strongly associated with severe cardiac and noncardiac malformations, while Type II lesions are more frequently associated with Down's syndrome, suggesting different timings of embryological interference.
Tenckhoff et al. (1973) conducted an observational in Complete form of persistent common atrioventricular canal (n=35). Type I morphology (free-floating undivided common anterior leaflet) vs. Type II morphology (divided common anterior leaflet attached to septum) was evaluated on Incidence of associated cardiac and noncardiac malformations. Type I persistent common atrioventricular canal was associated with high rates of other cardiac (90%) and noncardiac (80%) malformations, whereas Type II had more Down's syndrome (40%).
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