Key result
Genetic variants linked to inherited cardiomyopathies play a critical role in HF pathogenesis and progression.
Why the study?
Heart failure is driven by complex genetic factors, with cardiomyopathy being the most common genetic cause, prompting investigation into their shared genetic variants.
This review highlights the genetic variants linked to inherited cardiomyopathy and their role in the pathogenesis and progression of heart failure.
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May inform genetic evaluation in cardiomyopathy-linked HF; leaves open whether variants should guide therapy.
Kaviarasan et al. (2022) conducted a review in Heart failure and cardiomyopathy. Numerous genetic variants, particularly those associated with inherited cardiomyopathies, play a critical role in the pathogenesis and progression of heart failure.