Key result
Review outlines platelet roles in atherosclerosis and thrombosis, function testing, and current antiplatelet pharmacology.
This review summarizes the pathophysiology of platelets in coronary artery disease and the pharmacology of current antiplatelet therapies.
Synthesizes platelet pathophysiology and antiplatelet pharmacology in CAD; leaves open optimal testing strategies and novel agents for prospective trials.
Platelets play a key role in the pathophysiology of coronary artery disease and acute coronary syndromes. Our understanding of platelet function in thrombus formation has increased considerably, resulting in the development of clinically effective treatment strategies and identification of new targets. An underappreciated platelet function is their contribution toward acute and chronic inflammatory processes including atherogenesis. In this review, we discuss the role of platelets in atherosclerosis and thrombosis, platelet function testing, and the pharmacology of currently available antiplatelet drugs.
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Ibrahim et al. (2017) conducted a review in Coronary artery disease and acute coronary syndromes. Antiplatelet drugs was evaluated. This review discusses the role of platelets in atherosclerosis and thrombosis, platelet function testing, and the pharmacology of currently available antiplatelet drugs.
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