What question did this study set out to answer?

To determine the impact of outpatient pharmacist care interventions, delivered independently or collaboratively, on the clinical management of major cardiovascular disease risk factors.

September 12, 2011Archives of Internal Medicine

Impact of Pharmacist Care in the Management of Cardiovascular Disease Risk Factors

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Authors

VSValérie SantschiUniversity of Bern

Discussion

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Implication

Systematic review of randomized controlled trials shows pharmacist care reduces blood pressure and cholesterol in outpatients, indicating enhanced prevention through collaborative care.

Key Points

To determine the impact of outpatient pharmacist care interventions, delivered independently or collaboratively, on the clinical management of major cardiovascular disease risk factors.
Searched MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials for randomized controlled trials evaluating outpatient pharmacist interventions for cardiovascular risk factors.
Two reviewers independently abstracted data on interventions, which included patient education, reminder systems, risk factor screening, medication management, and prescriber feedback.
Estimated mean changes in blood pressure, total cholesterol, low-density lipoprotein cholesterol, and smoking cessation using random-effects models across 30 randomized controlled trials (N=11,765).
Pharmacist care was associated with a significant reduction in systolic blood pressure of -8.1 mm Hg (95% CI, -10.2 to -5.9) and diastolic blood pressure of -3.8 mm Hg (95% CI, -5.3 to -2.3; 19 studies, n=10,479).
Pharmacist interventions significantly lowered total cholesterol by -17.4 mg/L (95% CI, -25.5 to -9.2; 9 studies, n=1,121) and low-density lipoprotein cholesterol by -13.4 mg/L (95% CI, -23.0 to -3.8; 7 studies, n=924).
Pharmacist care significantly decreased the risk of smoking (relative risk, 0.77; 95% CI, 0.67 to 0.89; 2 studies, n=196), although substantial heterogeneity was observed across trials.

Cite This Study

Valérie Santschi (2011) studied this question.

synapsesocial.com/papers/6a0cfa60b31ab1d6e01e73b5 https://doi.org/10.1001/archinternmed.2011.399

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September 12, 2011Archives of Internal Medicine

Impact of Pharmacist Care in the Management of Cardiovascular Disease Risk Factors

View Full Paper

Ask AI

Bookmark

Authors

VSValérie SantschiUniversity of Bern

Discussion

Member takes

Implication

Systematic review of randomized controlled trials shows pharmacist care reduces blood pressure and cholesterol in outpatients, indicating enhanced prevention through collaborative care.

Key Points

To determine the impact of outpatient pharmacist care interventions, delivered independently or collaboratively, on the clinical management of major cardiovascular disease risk factors.
Searched MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials for randomized controlled trials evaluating outpatient pharmacist interventions for cardiovascular risk factors.
Two reviewers independently abstracted data on interventions, which included patient education, reminder systems, risk factor screening, medication management, and prescriber feedback.
Estimated mean changes in blood pressure, total cholesterol, low-density lipoprotein cholesterol, and smoking cessation using random-effects models across 30 randomized controlled trials (N=11,765).
Pharmacist care was associated with a significant reduction in systolic blood pressure of -8.1 mm Hg (95% CI, -10.2 to -5.9) and diastolic blood pressure of -3.8 mm Hg (95% CI, -5.3 to -2.3; 19 studies, n=10,479).
Pharmacist interventions significantly lowered total cholesterol by -17.4 mg/L (95% CI, -25.5 to -9.2; 9 studies, n=1,121) and low-density lipoprotein cholesterol by -13.4 mg/L (95% CI, -23.0 to -3.8; 7 studies, n=924).
Pharmacist care significantly decreased the risk of smoking (relative risk, 0.77; 95% CI, 0.67 to 0.89; 2 studies, n=196), although substantial heterogeneity was observed across trials.

Cite This Study

Valérie Santschi (2011) studied this question.

synapsesocial.com/papers/6a0cfa60b31ab1d6e01e73b5 https://doi.org/10.1001/archinternmed.2011.399

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