Key result
Genetically confirmed FH affects just 1.8% of premature STEMI patients, whereas classical risk factors dominate.
Why the study?
Familial hypercholesterolemia is an underdiagnosed genetic condition leading to premature CAD, but its prevalence in patients with premature STEMI has not been widely studied.
What is the prevalence of familial hypercholesterolemia in patients with premature STEMI?
Observational (n=56)
No
What is the prevalence of familial hypercholesterolemia in patients with premature STEMI?
The prevalence of familial hypercholesterolemia in premature STEMI is low (1.8%), while classical risk factors like smoking and obesity are highly prevalent, highlighting the need for aggressive secondary prevention and lipid-lowering therapy.
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Classical risks predominate in premature STEMI; leaves open selective FH screening by DLCN score.
Lorca et al. (2020) conducted an observational in Premature STEMI (n=56). The prevalence of genetically confirmed familial hypercholesterolemia in patients with premature STEMI was low (1.8%), while classical risk factors like smoking and high BMI were present in >80%.
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