Key result
Exercise testing modalities identify underlying disease mechanisms in PH.
Why the study?
Pulmonary hypertension often presents with non-specific symptoms such as dyspnea and exercise intolerance, making early diagnosis difficult before the onset of right heart dysfunction.
What is the role of exercise testing modalities in evaluating patients with pulmonary hypertension?
What is the role of exercise testing modalities in evaluating patients with pulmonary hypertension?
Exercise testing modalities provide valuable diagnostic and prognostic information in the evaluation of patients with pulmonary hypertension.
Supports exercise testing to identify PH mechanisms; leaves open prospective validation before routine adoption.
Pulmonary hypertension (PH), defined by a mean pulmonary artery pressure of >20 mm Hg, often presents with non-specific symptoms such as dyspnea and exercise intolerance, making it difficult to diagnose early before the onset of right heart dysfunction. Therefore, exercise testing can be of great utility for clinicians who are evaluating patients with an unclear etiology of exercise intolerance by helping identify the underlying mechanisms of their disease. The presence of PH is associated with adverse clinical outcomes, with distinct differences and patterns in the cardiovascular and ventilatory responses to exercise across various PH phenotypes. We discuss the role of exercise-invasive hemodynamic testing, cardiopulmonary exercise testing, and exercise stress echocardiography modalities across the spectrum of PH.
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Vaidy et al. (2024) conducted a review in Pulmonary Hypertension. Exercise testing was evaluated. Exercise testing modalities, including invasive hemodynamic testing, cardiopulmonary exercise testing, and stress echocardiography, help identify underlying mechanisms of disease in pulmonary hypertension.
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