Key result
A mechanical analysis method using intravascular ultrasound identified an optimized elastic modulus of 90.9-93.0 kPa in early atherosclerotic lesions versus 97.9-101.0 kPa in normal segments.
Population
Diseased arterial segments reconstructed from intravascular ultrasound images
Comparison
Mechanical analysis using finite element and… vs Normal arterial segments
Design
Other
Authors
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Hypothesis-generating for IVUS elasticity mapping in early atherosclerosis; requires prospective validation before any clinical adoption.
A novel computational method using intravascular ultrasound can quantitatively identify regional alterations in arterial wall elasticity associated with early atherosclerotic lesions.
Chandran et al. (2003) studied Atherosclerosis. Mechanical analysis using finite element and displacement sensitivity analysis from intravascular ultrasound images vs. Normal arterial segments was evaluated on Optimized elastic modulus. A mechanical analysis method using intravascular ultrasound identified an optimized elastic modulus of 90.9-93.0 kPa in early atherosclerotic lesions versus 97.9-101.0 kPa in normal segments.
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