Key result
In patients with a Brugada syndrome ECG pattern and normal echocardiography, 71% had abnormal right ventricular wall motion and 8% fulfilled diagnostic criteria for both Brugada syndrome and ARVD/C.
Observational (n=114)
No
There is a significant phenotypic overlap between Brugada syndrome and localized forms of ARVD/C, with 71% of BrS-ECG patients showing abnormal RV wall motion on angiography.
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Supports Brugada-ARVD/C overlap on imaging; hypothesis-generating and should not yet change practice.
Duthoit et al. (2012) conducted an observational in Brugada syndrome and Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) (n=114). Cardiac catheterization and quantitative biventricular contrast angiography vs. Localized ARVD/C patients and healthy controls was evaluated on Prevalence of overlap between Brugada syndrome and ARVD/C (fulfilling both ESC/WHF 2000 and HRS/EHRA 2005 criteria). In patients with a Brugada syndrome ECG pattern and normal echocardiography, 71% had abnormal right ventricular wall motion and 8% fulfilled diagnostic criteria for both Brugada syndrome and ARVD/C.
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