Association of revascularisation with low mortality in non-ST elevation acute coronary syndrome, a report from GUSTO IV-ACS
Why the study?
Does coronary revascularisation within 30 days reduce one-year mortality in patients with non-ST elevation acute coronary syndrome?
Population
7,496 patients with non-ST elevation acute coronary syndrome who survived at least 30 days.
Comparison
Coronary revascularisation within 30 days. vs Medical treatment without revascularisation…
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
May support early revascularisation in NSTE-ACS; leaves open causal confirmation by randomised trials.
Structured PICO
Does coronary revascularisation within 30 days reduce one-year mortality in patients with non-ST elevation acute coronary syndrome?
P
Population
7,496 patients with non-ST elevation acute coronary syndrome (documented by elevated cardiac troponin or transient/persistent ST-segment depression) who survived at least 30 days.
I
Intervention
Coronary revascularisation (CABG, PCI, or both) within 30 days.
C
Comparator
Medical treatment without revascularisation within 30 days.
O
Outcome
One-year mortality.hard clinical
Revascularisation within 30 days in patients with non-ST elevation acute coronary syndrome is associated with significantly improved one-year survival compared to medical therapy alone.
Limitations
- Patient selection bias in medically treated patients
Cite This Study
Ottervanger et al. (2004) studied this question.