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January 1, 2003Journal of Biological ChemistryOpen Access

The Paired Domain-containing Factor Pax8 and the Homeodomain-containing Factor TTF-1 Directly Interact and Synergistically Activate Transcription

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Authors

TPTina Di PalmaInstitute for Experimental Endocrinology and OncologyRNRoberto NitschAstraZeneca (Finland)AMAnna Mascia

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Palma et al. (2003) studied this question.

synapsesocial.com/papers/6a0d2e4c48a82a5ce309a83fhttps://doi.org/10.1074/jbc.m205977200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Distinct Functional Properties of Three Human Paired-Box-Protein, PAX8, Isoforms Generated by Alternative Splicing in Thyroid, Kidney and Wilms' Tumors1995 · 71 citations
  2. 2<i>Pax</i> genes and organogenesis1997 · 368 citations
  3. 3The Synergistic Activity of Thyroid Transcription Factor 1 and Pax 8 Relies on the Promoter/Enhancer Interplay2002 · 59 citations
  4. 4The tissue‐specific expression of the thyroglobulin gene requires interaction between thyroid‐specific and ubiquitous factors1990 · 92 citations
  5. 5Pax-8 protein levels regulate thyroglobulin gene expression1998 · 70 citations