Key result
Measuring biological ageing markers such as vascular stiffness may serve as a useful non-invasive screening tool to predict cardiovascular morbidity and mortality in older people.
Understanding normal cardiovascular aging and measuring vascular stiffness may help identify older individuals at risk for cardiovascular disease and guide risk factor modification.
Hypothesis-generating for vascular stiffness screening in older adults; prospective validation required before clinical adoption.
Summary The increase in the ageing population has generated much interest and research into what constitutes normal ageing. By identifying normal ageing processes it is hoped it will be possible to distinguish risk factors for the development of abnormal or premature ageing. This review discusses biological, structural and mechanical changes in the cardiovascular system with ageing that are thought to increase the risk of cardiovascular disease with ageing. Contributory factors are thought to be genetic and lifestyle related. Measurements of biological as opposed to chronological ageing such as vascular stiffness are explored as a possible useful predictor of cardiovascular morbidity and mortality, indicating its possible utilization as a non-invasive screening tool in older people. The identification of those at risk of cardiovascular disease and modification of risk factors may minimize interactions of the ageing process and therefore reduce the incidence of cardiovascular disease within the UK population.
No takes yet. Share an insight, caveat, or question.
Bolton et al. (2011) conducted a review in Cardiovascular disease in ageing. Measuring biological ageing markers such as vascular stiffness may serve as a useful non-invasive screening tool to predict cardiovascular morbidity and mortality in older people.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: