Key result
T-wave plus-minus ECG and anterior-posterior VCG patterns identify LV aneurysms with ~94% accuracy.
Why the study?
The study aimed to characterize the electrovectorcardiographic pattern of ventricular aneurysms in ischemic cardiopathy by analyzing cardiac ventricular repolarization.
Does electrovectorcardiographic analysis accurately identify left ventricular aneurysms in patients with ischemic heart disease?
Cross-Sectional (n=49)
Single-blind
No
Does electrovectorcardiographic analysis accurately identify left ventricular aneurysms in patients with ischemic heart disease?
Effect estimate: Sensitivity 95% (95% CI 77.1-99.8)
p-value: p=<0.0001
Electrovectorcardiographic parameters, specifically T-wave patterns in V2-V4, demonstrate high diagnostic accuracy for identifying left ventricular aneurysms in patients with ischemic heart disease.
T-wave patterns may aid LV aneurysm detection in IHD; hypothesis-generating and requires prospective validation before practice change.
The aim was to characterize the electrovectorcardiographic pattern of ventricular aneurysms in ischemic cardiopathy by analyzing the cardiac ventricular repolarization. The medical records of 2,670 individuals were analyzed in this cross-sectional study. A test phase included 33 patients who underwent transthoracic echocardiogram with ultrasonic enhancing agent, electrocardiogram, and vectorcardiogram (aneurysm group - n = 22, and akinesia group - n = 11). In the validation phase, cardiac magnetic resonance imaging established the left ventricle segmental contractility in 16 patients who underwent electrocardiographic and vectorcardiographic tests (aneurysm group, n = 8, and akinesia group, n = 8). The variables studied were the presence of the T-wave plus-minus pattern and the T-wave loop anterior-posterior pattern in V2–V4. The diagnostic indices used were sensitivity, specificity, and predictive values, with their respective 95% confidence intervals. During the test and validation phases, the analysis of the presence of the T-wave plus-minus pattern identified the aneurysm group with a sensitivity of 91% vs. 87% and specificity of 91% vs. 87% ( p < 0.0001 vs. p = 0.01), respectively. Meanwhile, the T-wave loop anterior-posterior pattern evidenced sensitivity of 95% vs. 77% and specificity of 91% vs. 87% ( p < 0.0001 vs. p = 0.04), respectively. The electrovectorcardiographic parameters showed high accuracy for recognizing left ventricular aneurysms in ischemic heart disease.
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Varoni et al. (2023) conducted a cross-sectional in Left ventricular aneurysm in ischemic heart disease (n=49). Electrocardiogram and Vectorcardiogram vs. Akinesia group was evaluated on Identification of left ventricular aneurysm using T-loop anterior-posterior pattern on vectorcardiogram (Sensitivity 95%, 95% CI 77.1-99.8, p=<0.0001). The T-wave plus-minus electrocardiogram pattern and anterior-posterior T-wave loop vectorcardiogram pattern identified left ventricular aneurysms with 91% and 94% accuracy, respectively.
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