Key result
ST-segment elevation in lead aVR significantly predicted 3-vessel or left main trunk disease in acute coronary syndrome patients (49% vs 3% in UAP, 59% vs 6% in AMI; p<0.01).
Why the study?
Does ST-segment elevation in lead aVR predict multi-vessel coronary artery disease and severe pump failure in patients with acute coronary syndrome?
Observational (n=705)
No
Does ST-segment elevation in lead aVR predict multi-vessel coronary artery disease and severe pump failure in patients with acute coronary syndrome?
ST-segment elevation in lead aVR during acute coronary syndrome is a strong, easily accessible predictor of severe multi-vessel coronary artery disease and poor clinical outcomes.
Answers are grounded in this paper and cite their sources.
ST-segment elevation in aVR was associated with multivessel or left main disease in ACS; hypothesis-generating for risk stratification pending prospective validation.
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Sakai et al. (1998) conducted an observational in Acute coronary syndrome (Unstable angina pectoris and Acute myocardial infarction) (n=705). ST-segment elevation ≥0.1mV in lead aVR vs. No ST-segment elevation in lead aVR (<0.1mV) was evaluated on Incidence of 3-vessel or left main trunk coronary artery disease (UAP cohort) (p=<0.01). ST-segment elevation in lead aVR significantly predicted 3-vessel or left main trunk disease in acute coronary syndrome patients (49% vs 3% in UAP, 59% vs 6% in AMI; p<0.01).
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