What does this research mean for the field?

While botanical extracts demonstrate pharmacological efficacy in modulating key inflammatory signaling cascades in asthma, the predominant reliance on unrefined preparations necessitates greater chemical standardization and rigorous mechanistic validation for clinical translation. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This review aims to synthesize the pharmacological effects of botanical extracts in asthma management and identify research gaps.

May 20, 2026NutrientsOpen Access

Harnessing Botanical Extracts for Asthma Therapy: A Scoping Review of Molecular Mechanisms and the Strategic Utility of Experimental Models (2005–2025)

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This review aims to synthesize the pharmacological effects of botanical extracts in asthma management and identify research gaps.
Systematic literature search from 2005 to 2025
Focused analysis of preclinical studies from 2016 to 2025
Evaluation of in vitro and in vivo models used for studying botanical extracts.
Most studies use crude botanical preparations; few employ characterized compounds.
Significant gap in chemical standardization among studies.
Identifies pathways for clinical application of botanical extracts.

Authors

JLJ J LeeKorea Research Institute of Bioscience and Biotechnology CJChang Hyeon JeonKorea Research Institute of Bioscience and Biotechnology SPSoo-Jin ParkKorea Research Institute of Bioscience and Biotechnology

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Implication

Scoping review evaluates botanical extracts' efficacy and underlying mechanisms in asthma, suggesting clinical applications.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4ec0f03e14405aa99ec9 https://doi.org/10.3390/nu18101604

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Harnessing Botanical Extracts for Asthma Therapy: A Scoping Review of Molecular Mechanisms and the Strategic Utility of Experimental Models (2005–2025)

Key Points

Discussion

Implication

Cite This Study

Harnessing Botanical Extracts for Asthma Therapy: A Scoping Review of Molecular Mechanisms and the Strategic Utility of Experimental Models (2005–2025)

Key Points

Discussion

Implication

Cite This Study

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