Abstract Engaging students in integrative and organismal biology often requires instructional approaches that balance disciplinary rigor with accessibility and curiosity. Extraordinary traits in real organisms, such as regeneration in axolotls, echolocation in bats, or cryptobiosis in tardigrades, offer compelling entry points for exploring adaptation, evolutionary trade-offs, and the diversity of life. This article describes a curriculum activity, Biology of Superpowers, designed to leverage these traits to promote engagement, reinforce evolutionary concepts, and develop science communication skills in courses spanning introductory and upper-level biology. In this activity, students select a biological “superpower,” investigate its functional mechanisms and adaptive significance, and communicate their findings in a creative, public-facing format. An optional extension invites students to connect their chosen trait to superheroes or fictional characters, prompting critical evaluation of scientific accuracy and common misconceptions in popular media. The activity has been implemented in two distinct settings: an introductory non-majors Diversity of Life course and an upper-level Evolution course for biology majors. These dual contexts illustrate the adaptability of the assignment across levels. In the non-majors course, students emphasized accessible explanations and broad connections to survival and reproduction for general audiences, whereas majors more often incorporated mechanistic detail, comparative thinking, and consideration of constraints and trade-offs. Assessment is guided by revised rubrics that emphasize biological explanation, evolutionary reasoning appropriate to course level, clarity of communication, and use of evidence. Student artifacts are presented as illustrative examples of engagement with the activity rather than as formal evidence of learning gains. To strengthen implementation, the revised instructor and student materials include explicit prompts related to source evaluation, image attribution, appropriate AI use, and avoidance of common evolutionary misconceptions such as teleological reasoning or framing evolution as only about survival. Blank organizer templates are also provided to support scaffolding across course contexts. Together, these materials position Biology of Superpowers as a flexible curriculum model for teaching integrative and organismal biology by pairing curiosity-driven content with evolutionary thinking, evidence use, and science communication.
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