A portable acoustic biosensing platform combined with paper-based capillary fluidics for the rapid detection of antibodies in serum

Dimitra Chronaki; Stylianos Grammatikos; Angelos Ntimtsas; Marios Matsis; Orestis F. Kokolakis; Konstantina Alexaki; Zoi Pournara; Achilleas Tsortos; Alexandros Zafiropoulos; Electra Gizeli

doi:10.1039/d6an00114a

January 1, 2026The AnalystOpen Access

A portable acoustic biosensing platform combined with paper-based capillary fluidics for the rapid detection of antibodies in serum

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Key Points

This research aims to develop a portable platform for the efficient detection of antibodies in serum samples.
Developed a portable biosensing platform that integrates a pocket-size network analyzer with paper-based fluidics.
Utilized a regenerable sensing surface to enhance detection capabilities.
Tested the platform's effectiveness in rapidly detecting antibodies near or at the point-of-care.
Achieved quantitative antibody detection with the low-cost platform.
Demonstrated the capability of the system for use in real-time scenarios at point-of-care.
Detected antibodies effectively with a simple interface, enabling easier access to testing.

Implication

Demonstrates rapid antibody detection in serum using a portable biosensing platform, indicating its utility at point-of-care.

Abstract

. This portable, low-cost platform, combining a pocket-size network analyzer with disposable paper fluidics and a regenerable sensing surface, offers a promising solution for quantitative antibody detection near or at the point-of-care.

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Cite This Study

Chronaki et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4ee2f03e14405aa9a18c https://doi.org/10.1039/d6an00114a

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A portable acoustic biosensing platform combined with paper-based capillary fluidics for the rapid detection of antibodies in serum

Key Points

Implication

Abstract

Discussion

Cite This Study

A portable acoustic biosensing platform combined with paper-based capillary fluidics for the rapid detection of antibodies in serum

Key Points

Implication

Abstract

Discussion

Cite This Study

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