Key result
Transhumeral amputation for synovial sarcoma with venous invasion yields no recurrence or metastasis at 12 months.
Case Report (n=1)
No
Transhumeral amputation with adequate margins can be an effective treatment for synovial sarcoma with local venous invasion, preventing recurrence at 12 months.
May warrant consideration of amputation for synovial sarcoma with venous invasion; leaves open need for longer-term and comparative data.
Synovial sarcoma is a high-grade malignant soft tissue tumor associated with poor survival that mainly occurs in young adults and adolescents. We report a rare case of forearm synovial sarcoma with local venous invasion in an 87-year-old woman. She presented with a painful enlarging mass in the left forearm. Contrast-enhanced magnetic resonance imaging revealed a 20×10×7 cm lobulated mass involving both the anterior and posterior compartments. Positron emission tomography-computed tomography showed no distant metastasis or regional lymph node involvement. Histological examination confirmed grade 2 monophasic synovial sarcoma. Abnormal enlargement of the cephalic, median cubital, basilic, and brachial veins was observed 5 cm proximal to the tumor. Transhumeral amputation was performed with a 2-cm surgical margin from the proximal end of the enlarged vessels. No tumor cells were identified at the amputation margin. At 12 months after surgery, the patient showed no recurrence or metastasis.
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Choi et al. (2026) conducted a case report in Synovial sarcoma with local venous invasion (n=1). Transhumeral amputation was evaluated on Recurrence or metastasis. In an 87-year-old woman with a large forearm synovial sarcoma showing local venous invasion, transhumeral amputation resulted in no recurrence or metastasis at 12 months postoperatively.
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