Case report details a neuroendocrine tumor in a young male, highlighting symptoms and treatment outcomes.
Neuroendocrine tumors (NETs) are rare neoplasms that most commonly occur in the gastrointestinal tract, lungs, and pancreas but may arise anywhere where there are neuroendocrine cells within the body. When neuroendocrine tumors metastasize to the liver, patients present with carcinoid syndrome, a group of symptoms characterized by flushing, diarrhea, and right-sided heart disease. However, many NETs do not cause carcinoid syndrome, sometimes leading to a unique clinical presentation. Patients may present with symptoms of appendicitis, ovarian torsion, or be completely asymptomatic. We report a case of a 25-year-old male with a Grade 1 neuroendocrine tumor of the appendix, who underwent a laparoscopic appendectomy. Determining whether the NET has metastasized is crucial for proper long-term treatment of patients post-appendectomy.
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Zipfel et al. (2026) studied this question.
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