What question did this study set out to answer?

To report a case of a misdiagnosed mediastinal mass originally thought to be thymic carcinoma, later identified as classical Hodgkin lymphoma.

C78-39 A Mediastinal Mass Mystery: Suspected Thymic Carcinoma With a Twist

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To report a case of a misdiagnosed mediastinal mass originally thought to be thymic carcinoma, later identified as classical Hodgkin lymphoma.
Patient presented with a mediastinal mass discovered incidentally via chest x-ray and CT imaging.
Neoadjuvant chemotherapy was recommended before surgery due to mass size and interdisciplinary discussions.
A CT-guided biopsy was performed to confirm the diagnosis, revealing classical Hodgkin lymphoma.
Initial imaging suggested thymic carcinoma with significant mass dimensions (15 x 6 x 13 cm).
Biopsy confirmed classical Hodgkin lymphoma (nodular sclerosis subtype); patient was diagnosed with stage IVA disease.
Post-treatment PET-CT showed significant reduction of the mediastinal mass (8.9 x 5.4 cm, SUVmax 2.1) and decrease in pleural metastasis SUVmax to 1.0.

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This case report unveils a misdiagnosis of thymic carcinoma in a patient with classical Hodgkin lymphoma, highlighting diagnostic challenges.

Kolasa et al. (2026) studied this question.

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This case report unveils a misdiagnosis of thymic carcinoma in a patient with classical Hodgkin lymphoma, highlighting diagnostic challenges.