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May 20, 2026Journal of Nutrition and MetabolismOpen Access

A Review of Curcumin in Chronic Disease Management: Anti‐Inflammatory Pathways, Antioxidant Activity, and Therapeutic Advances

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Authors

SMSammra MaqsoodFAFarhang Hameed AwlqadrIUIffat Ullah

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Overview

Review discusses curcumin's anti-inflammatory impact on chronic diseases, highlighting therapeutic advances and challenges.

Key Points

  • This review aims to explore the anti-inflammatory properties of curcumin and its therapeutic applications in chronic diseases.
  • Reviewed molecular mechanisms of curcumin's anti-inflammatory activities.
  • Analyzed the interaction of curcumin with inflammatory signaling pathways.
  • Highlighted advancements in drug administration methods for enhancing curcumin bioavailability.
  • Curcumin effectively downregulates proinflammatory cytokines and decreases oxidative stress.
  • It significantly blocks the NF-κB pathway and reduces COX-2 and LOX enzyme levels.
  • Encouraging potential observed in chronic conditions such as rheumatoid arthritis and inflammatory bowel disease.

Cite This Study

Maqsood et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4fbff03e14405aa9b2d0https://doi.org/10.1155/jnme/9985642
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