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May 20, 2026American Journal of Respiratory and Critical Care Medicine

B72-20 Mediastinal Lymphadenopathy Due to Disseminated Cryptococcus in a Patient With Newly Diagnosed HIV/AIDS

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Authors

VBV Z BiscuitwalaSRS Ali Riaz

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Overview

Case presentation reveals cryptococcal infection mimicking tuberculosis in an HIV/AIDS patient, highlighting diagnostic challenges.

Key Points

  • This case aims to illustrate a rare presentation of disseminated cryptococcosis with mediastinal lymphadenopathy in an HIV patient.
  • Detailed clinical evaluation of a 44-year-old male with recently diagnosed HIV.
  • Endobronchial ultrasound-guided fine-needle aspiration for lymph node sampling.
  • Cultures from blood and cerebrospinal fluid confirmed the presence of Cryptococcus neoformans.
  • Detectable cryptococcus in mediastinal lymph nodes led to early antifungal treatment.
  • Successful management of elevated intracranial pressure with lumbar punctures.
  • Patient's fungal infection severity illustrated the need for targeted therapies in HIV.

Cite This Study

Biscuitwala et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4fbff03e14405aa9b2f3https://doi.org/10.1093/ajrccm/aamag162.4309
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