Neuro-immune axis regulates humoral immune response: an interdisciplinary exploration from bench to bedside

Key Points

• Examines how the neuro-immune axis influences humoral immune responses, focusing on B cell regulation.
• Systematic review of research on neuro-immune interactions affecting B cells.
• Analysis of mechanisms involving the sympathetic and parasympathetic nervous systems.
• Discussion of potential applications in vaccine adjuvants and autoimmune disease treatments.
• Neuro-immune interactions regulate B cell activation and proliferation through specific receptor pathways.
• Acute stress enhances, while chronic stress suppresses humoral immune responses.
• Vagus nerve stimulation shows promise in modulating immune reactions and developing new therapies.