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May 20, 2026American Journal of Respiratory and Critical Care Medicine

B69-08 Diagnostic Correlation Between High-resolution Computed Tomography Patterns and Sputum Gene Xpert MTB/RIF Results in Pulmonary Tuberculosis: A Five-year Retrospective Study in Cebu City, Philippines

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Authors

RVR Villarubia-AbellaGPG Pepito

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Overview

Retrospective cohort study evaluates HRCT and Gene Xpert associations in pulmonary tuberculosis, indicating diagnostic utility.

Key Points

  • The study aims to evaluate the correlation between HRCT patterns and Gene Xpert MTB/RIF results in pulmonary tuberculosis patients.
  • Conducted a five-year retrospective cohort study involving 122 patients with pulmonary tuberculosis admitted from January 2020 to January 2024.
  • Reviewed clinical, demographic, and HRCT variables and correlated them with sputum Gene Xpert MTB/RIF results.
  • Performed univariate logistic regression to identify HRCT features predictive of microbiologic confirmation.
  • 37 out of 122 patients (30%) tested positive for Gene Xpert.
  • Cavities exhibited a significant association with PTB positivity (OR = 5.0, p < 0.001).
  • Tree-in-bud opacities (OR = 3.25, p = 0.043) and consolidation (OR = 2.76, p = 0.018) were also predictive of PTB positivity.

Cite This Study

Villarubia-Abella et al. (2026) studied this question.

synapsesocial.com/papers/6a0d50cdf03e14405aa9ce73https://doi.org/10.1093/ajrccm/aamag162.6731
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