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May 20, 2026Cureus0 citationsOpen Access

Fatal Colonic Perforation Secondary to Non-typhoidal Salmonella Infection in an Immunocompetent Elderly Patient

MAMuhammad Zulfadhli Nor AzmiUDUmmi Nadira Daut

Key Points

  • This report aims to describe the rare occurrence of fatal colonic perforation caused by non-typhoidal Salmonella in an immunocompetent elderly patient.
  • Case report of an elderly patient with Salmonella gastroenteritis leading to colonic perforation.
  • Clinical evaluation and surgical intervention following perforation.
  • Postoperative observation for complications and outcomes.
  • Patient developed fatal multiorgan failure following surgery.
  • Complications included intra-abdominal sepsis post colonic perforation.
  • Highlights the need for early diagnosis and surgical intervention in severe cases.

Abstract

Salmonella is one of the leading foodborne pathogens worldwide. Their serotypes can be classified into typhoidal, which are known to cause enteric fever, and non-typhoidal, commonly known to cause gastroenteritis or food poisoning. Salmonella gastroenteritis is typically self-limiting, and most patients recover within a few days to a week without treatment. Intestinal perforation is an exceptionally rare and fatal complication. Here, we report a case of Salmonella gastroenteritis complicated by colonic perforation. Postoperatively, the patient succumbed due to multiorgan failure and intra-abdominal sepsis. This case highlights that even non-typhoidal Salmonella infection in an immunocompetent host may lead to catastrophic complications. Early recognition of clinical deterioration and timely surgical intervention are crucial to improve outcomes.

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Cite This Study

Azmi et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5100f03e14405aa9d31fhttps://doi.org/10.7759/cureus.109067
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