C48-46 Diffuse Alveolar Hemorrhage as a Manifestation of Choriocarcinoma Syndrome in a Young Male

Testicular germ cell tumors are the most common cause of solid-tumor malignancy in men between 20- and 40-years-old. Choriocarcinoma is a rare and highly malignant subtype. The five-year survival of choriocarcinoma is favorable with cisplatin-based chemotherapy; however, there is a high risk of mortality with advanced disease. A particularly dangerous time period is during chemotherapy initiation. We describe a case of a 24-year-old male who presented with choriocarcinoma syndrome—a rare phenomenon that leads to diffuse alveolar hemorrhage and acute respiratory distress. This is a consequence of the effect chemotherapy has on metastatic lesions in the lungs. Our goal is to educate physicians about the risk factors and clinical manifestations of choriocarcinoma syndrome. We aim to promote strategies for prevention and early identification of this consequential complication of an otherwise treatable disease. This abstract is funded by: none