Key result
Immunocytochemical analysis of rat skeletal muscle demonstrated at least two immunochemically distinct types of myosin and four types of muscle fibers (white, intermediate, and two red).
Immunocytochemical analysis demonstrates that more than one isoenzyme of myosin can exist in a single muscle, allowing individual fiber types to be recognized by immunological differences.
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Recognizes immunologic myosin heterogeneity in rat fibers; leaves open translation to human muscle physiology or disease.
Gauthier et al. (1977) studied Skeletal muscle fiber types. Immunocytochemical analysis using fluorescein-labeled immunoglobulin against purified chicken pectoralis myosin was evaluated on Localization of myosin with respect to individual fibers. Immunocytochemical analysis of rat skeletal muscle demonstrated at least two immunochemically distinct types of myosin and four types of muscle fibers (white, intermediate, and two red).