Coronary microvascular dysfunction as a plausible convergent mechanism in cancer therapy-related MINOCA: evidence synthesis and a call for diagnostic standardization

Key Points

• This research aims to explore how coronary microvascular dysfunction contributes to cancer therapy-related MINOCA (myocardial infarction without obstructive coronary arteries).
• Performed evidence synthesis to review existing literature on coronary microvascular dysfunction and MINOCA in the context of cancer therapy.
• Identified gaps in current diagnostic approaches for MINOCA arising from cancer treatments.
• Called for standardized diagnostic criteria to improve patient outcomes.
• Found that coronary microvascular dysfunction is a common mechanism observed in patients with cancer therapy-related MINOCA.
• Highlighted the need for standardized diagnostic approaches to better identify and treat affected patients.