Key result
Mechanical stress, tissue stiffness, and topography drive myofibroblast transdifferentiation and cardiac fibrosis after MI.
Design
Review
Authors
Loading...
Mechanical cues may shape post-MI fibrosis progression; leaves open mechanotherapeutic targets for prospective trials.
Key points are not available for this paper at this time.
Kim et al. (2017) studied this question. Mechanical stress, tissue stiffness, and topography regulate myofibroblast transdifferentiation and drive the dynamics of cardiac fibrosis following myocardial infarction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: