Key result
Color M-mode tissue Doppler imaging accurately assessed the nonuniformity of transmural velocities and correlated significantly with segment shortening during ischemia and reperfusion.
Why the study?
Does color M-mode tissue Doppler imaging accurately assess transmural myocardial velocities and ischemia-induced dysfunction in an open-chest dog model?
Population
13 open-chest dogs
Comparison
15 minutes of left anterior descending coronary… vs Baseline state and non-ischemic posterior wall
Design
Preclinical
Follow-up
120 minutes of reperfusion
Authors
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Validates tissue Doppler for transmural assessment in canine ischemia models; leaves open clinical translation.
Does color M-mode tissue Doppler imaging accurately assess transmural myocardial velocities and ischemia-induced dysfunction in an open-chest dog model?
Color M-mode tissue Doppler imaging is an accurate method to assess the nonuniformity of transmural velocities and quantify ischemia-induced regional myocardial dysfunction in a preclinical model.
Dérumeaux et al. (2000) studied Acute ischemia and reperfusion (n=13). Color M-mode tissue Doppler imaging (TDI) was evaluated on Transmural distribution of myocardial velocities and severity of dysfunction. Color M-mode tissue Doppler imaging accurately assessed the nonuniformity of transmural velocities and correlated significantly with segment shortening during ischemia and reperfusion.
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