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July 1, 1977Circulation185 citationsOpen Access

The pulsed Doppler coronary artery catheter preliminary report of a new technique for measuring rapid changes in coronary artery flow velocity in man.

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JCJason ColeCHCraig J. Hartley

Key Result

A new pulsed Doppler coronary artery catheter accurately measured coronary flow velocity (r=0.99), demonstrating that flow increases following contrast injection are limited by coronary stenosis.

Study Design

Type

Observational

Structured PICO

Does a pulsed Doppler coronary artery catheter accurately measure rapid changes in coronary artery flow velocity in patients undergoing diagnostic coronary arteriography?

P
Population
Patients undergoing diagnostic coronary arteriography
I
Intervention
Pulsed Doppler coronary artery catheter
O
Outcome
Instantaneous changes in coronary artery blood flow velocitysurrogate

A new pulsed Doppler catheter accurately measures coronary flow velocity and may provide a useful method for assessing hemodynamically significant stenosis.

Main Result

Effect estimate: r=0.99

Abstract

A new catheter which measures instantaneous changes in coronary artery blood flow velocity is described. The linear relationship between flow velocity is described. The linear relationship between flow velocity measured with the catheter and volume flow through small arteries is documented with a correlation coefficient of 4=0.99. Coronary flow velocity has been measured from the proximal right and left coronary arteries and aortic ostia of saphenous vein bypass grafts in patients undergoing diagnostic coronary arteriography. The increase in coronary flow following injection of contrast media in normal coronary arteries is similar to the increase in coronary flow reported following near-maximum exercise. This increased flow response following injection of contrast media is severly limited by coronary artery stenosis and may provide a useful method for assessing hemodynamically significant stenosis in patients with coronary artery disease.

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Cite This Study

Cole et al. (1977) conducted an observational in Coronary artery disease. Pulsed Doppler coronary artery catheter was evaluated on Correlation between flow velocity measured with the catheter and volume flow (r=0.99). A new pulsed Doppler coronary artery catheter accurately measured coronary flow velocity (r=0.99), demonstrating that flow increases following contrast injection are limited by coronary stenosis.

synapsesocial.com/papers/6a0d642748a82a5ce309b6d2https://doi.org/10.1161/01.cir.56.1.18
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