Key result
Calcific aortic stenosis is an inflammatory, atheromatous disease that may soon be modifiable with medical therapies to slow its progression and reduce the need for surgery.
Design
Review
Highlights the evolving understanding of calcific aortic stenosis as an active, atheromatous process rather than just passive wear and tear, opening avenues for medical therapy.
Calcific aortic stenosis is not the result of decades of wear and tear alone. Rather, it is being increasingly recognized as an inflammatory, atheromatous, and potentially modifiable disease. Exciting new research suggests that medical therapies may soon be available to retard its progression and reduce the need for surgery.
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Novaro et al. (2003) studied this question. Calcific aortic stenosis is an inflammatory, atheromatous disease that may soon be modifiable with medical therapies to slow its progression and reduce the need for surgery.
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