Key result
Presumed media calcifications occur in 32% of older aortic dissection patients, mostly in chronic cases.
Why the study?
Can contrast-enhanced CT visualize media calcifications in patients aged 60 and older with aortic dissection?
Observational (n=69)
No
Can contrast-enhanced CT visualize media calcifications in patients aged 60 and older with aortic dissection?
Contrast-enhanced CT can visualize presumed media calcifications in patients with aortic dissection, which appear more frequently in chronic compared to acute cases.
CT visualization of presumed media calcifications in aortic dissection is feasible but hypothesis-generating; does not yet inform management or prognosis.
OBJECTIVES: To investigate the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications in a consecutive series of patients with aortic dissection who underwent contrast-enhanced CT. METHODS: The study population compromised of 69 consecutive subjects aged 60 years and older with a contrast-enhanced CT scan demonstrating an aortic dissection. All CT scans were evaluated for the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications by two experienced observers. Between observer reliability was evaluated by using Cohen's Kappa. Differences between groups were tested using unpaired T test and Chi-square test. RESULTS: Presumed media calcifications were observed in 22 (32%) patients of 60 years and older and were found more frequently in chronic aortic dissection (N = 12/23, 52%) than in acute aortic dissection (N = 10/46, 22%). CONCLUSION: As the intima has been torn away by the aortic dissection it is highly likely that CT scans can visualize the calcifications in the tunica media of the aorta.
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Jong et al. (2014) conducted an observational in Aortic dissection (n=69). Contrast-enhanced CT was evaluated on Frequency of presumed media calcifications. Presumed media calcifications were observed on CT scans in 32% of patients aged 60 years and older with aortic dissection, occurring more frequently in chronic (52%) than acute (22%) cases.
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