What is the clinical evidence from this study?

Study design: Review. Population: Aortic and large artery stiffness.

What question did this study set out to answer?

To review current methods for measuring aortic and large artery stiffness and their clinical implications.

May 1, 1990Clinical CardiologyOpen Access

Aortic and large artery stiffness: Current methodology and clinical correlations

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Key result

Aortic and large artery stiffness increases progressively with age, accelerates in women post-menopause, and correlates with coronary disease, diabetes mellitus, and hypertension.

Design

Review

Authors

RHRoger B. HicklerUniversity of Massachusetts Chan Medical School

Discussion

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Implication

May support stiffness assessment for CV risk in aging and postmenopausal patients; leaves open whether modification alters outcomes.

Key Points

To review current methods for measuring aortic and large artery stiffness and their clinical implications.
Three methodologies for assessing stiffness: pulse wave velocity, imaging techniques, and Windkessel model analysis.
Examined correlations with factors like age, sex, atherosclerosis, coronary disease, diabetes, and hypertension.
Increased stiffness correlates with aging and structural changes, particularly after menopause in women.
Advanced atherosclerosis shows a complex relationship with stiffness, particularly in severe cases.
Diabetes and hypertension contribute to arterial stiffness without direct structural changes.

PICO

Population

Aortic and large artery stiffness

This review summarizes methodologies for measuring arterial stiffness and its clinical correlations with age, sex, and cardiovascular diseases.

Cite This Study

Roger B. Hickler (1990) conducted a review in Aortic and large artery stiffness. Aortic and large artery stiffness increases progressively with age, accelerates in women post-menopause, and correlates with coronary disease, diabetes mellitus, and hypertension.

synapsesocial.com/papers/6a0d6d7188250cfcc2a4f014 https://doi.org/10.1002/clc.4960130504

View Full Paper

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Aortic and large artery stiffness: Current methodology and clinical correlations

Discussion

Member takes

Implication

Key Points

PICO

Cite This Study

Aortic and large artery stiffness: Current methodology and clinical correlations

Discussion

Member takes

Implication

Key Points

PICO

Cite This Study

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Also Consider