Key result
Aortic vascular calcification was present in 90% of pre-dialysis CKD patients and correlated positively with age (r=0.50, P<0.001), triglycerides (r=0.47, P=0.002), and pulse wave velocity.
Population
48 pre-dialysis patients with chronic kidney disease, median age 64.5 years, 71% male, 54% diabetic.
Design
Cross-sectional
Authors
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Does not support practice change in pre-dialysis CKD; leaves open causal links to stiffness and need for longitudinal data.
Cross-Sectional (n=48)
In pre-dialysis CKD patients, there is a high prevalence of vascular calcification which correlates with arterial stiffness and inversely with femoral bone mineral density.
Toussaint et al. (2007) conducted a cross-sectional in chronic kidney disease (n=48). Aortic vascular calcification was present in 90% of pre-dialysis CKD patients and correlated positively with age (r=0.50, P<0.001), triglycerides (r=0.47, P=0.002), and pulse wave velocity.
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