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January 18, 1999The Journal of Experimental MedicineOpen Access

Transforming Growth Factor β1 Inhibits Fas Ligand Expression and Subsequent Activation-induced Cell Death in T Cells via Downregulation of c-Myc

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Authors

LGLaurent GenestierUniversité Claude Bernard Lyon 1SKShailaja KasibhatlaBoundless Bio (United States)TBThomas BrunnerMedical University of Graz

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Cite This Study

Genestier et al. (1999) studied this question.

synapsesocial.com/papers/6a0da73388250cfcc2a50cf5https://doi.org/10.1084/jem.189.2.231
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Also Consider

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  1. 1TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes1997 · 130 citations
  2. 2Down-modulation of c-myc expression induces apoptosis of B lymphocyte models of tolerance via clonal deletion1997 · 40 citations
  3. 3Effects of transforming growth factor- beta on human lymphokine-activated killer cell precursors. Autocrine inhibition of cellular proliferation and differentiation to immune killer cells.1988 · 116 citations
  4. 4Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.1989 · 161 citations
  5. 5Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 11991 · 235 citations