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January 18, 1999The Journal of Experimental MedicineOpen Access

Regulatory T Cells in the Control of Autoimmunity: the Essential Role of  Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes

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Authors

BSBenedict SeddonInstitute of Infection and ImmunityDMDon MasonConsejo Superior de Investigaciones Científicas

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Seddon et al. (1999) studied this question.

synapsesocial.com/papers/6a0dad57fb8c7be8ffba7aa3https://doi.org/10.1084/jem.189.2.279
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4<sup>+</sup> T cells1991 · 209 citations
  2. 2Purification of human C3b inactivator by monoclonal-antibody affinity chromatography1982 · 122 citations
  3. 3T Helper Cell Subsets in Insulin-Dependent Diabetes1995 · 599 citations
  4. 4Transforming Growth Factor β (TGF-β)-dependent Inhibition of T Helper Cell 2 (Th2)-induced Autoimmunity by Self–Major Histocompatibility Complex (MHC) Class II–specific, Regulatory CD4+ T Cell Lines1997 · 150 citations