Key result
Normalized ascending aortic flow displacement correlates with LV mass index and relative wall mass in AS.
Why the study?
Do 4D-flow MRI-derived abnormal blood flow patterns and wall shear stress associate with left ventricular remodeling in patients with aortic stenosis?
Observational (n=74)
Do 4D-flow MRI-derived abnormal blood flow patterns and wall shear stress associate with left ventricular remodeling in patients with aortic stenosis?
p-value: p=0.0058
4D-flow MRI demonstrates that abnormal blood flow patterns and wall shear stress in the ascending aorta are associated with left ventricular remodeling in patients with aortic stenosis.
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Should not yet change aortic stenosis management; leaves open whether 4D-flow MRI aids LV remodeling assessment.
Knobelsdorff‐Brenkenhoff et al. (2016) conducted an observational in Aortic stenosis (n=74). 4-dimensional-flow magnetic resonance imaging vs. Healthy controls was evaluated on Association of normalized flow displacement with LV mass index and relative wall mass (p=0.0058). In patients with aortic stenosis, normalized flow displacement in the ascending aorta was significantly associated with LV mass index (P=0.0058) and relative wall mass (P=0.0283).
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