Key result
Novel ABPM index Sf/Am positively correlates with LVEF in heart failure patients.
Why the study?
A simple ambulatory measure of cardiac function could be helpful for monitoring heart failure patients, but its association with LVEF was unknown.
Does the novel pulse waveform index Sf/Am measured by multisensor-ABPM correlate with LVEF in heart failure patients?
Observational (n=20)
Does the novel pulse waveform index Sf/Am measured by multisensor-ABPM correlate with LVEF in heart failure patients?
The novel noninvasive pulse waveform index Sf/Am measured by multisensor-ABPM correlates with LVEF and may be a useful surrogate for estimating cardiac function in heart failure patients.
A simple ambulatory measure of cardiac function could be helpful for monitoring heart failure patients. The purpose of this paper was to determine whether a novel pulse waveform analysis using data obtained by our developed multisensor-ambulatory blood pressure monitoring (ABPM) device, the 'Sf/Am' ratio, is associated with echocardiographic left ventricular ejection fraction (LVEF). Multisensor-ABPM was conducted twice at baseline in 20 heart failure (HF) patients with HF-reduced LVEF or HF-preserved LVEF (median age 66 years, male 65%) and over a 6- to 12-month follow-up after patient-tailored treatment. We assessed the changes in the pulse waveform index Sf/Am and LVEF that occurred between the baseline and follow-up. The Sf/Am consists of the area of the ejection part in the square forward wave (Sf) and the amplitude of the measured wave (Am). We divided the patients into the recovered (n = 11) and not-recovered (n = 9) groups defined by a ≥10% increase in LVEF. Although the ambulatory BP levels and variabilities did not change in either group, the Sf/Am increased significantly in the recovered group (baseline 21.4 ± 4.5; follow-up, 25.6 ± 3.7, P = 0.004). The not-recovered group showed no difference between the baseline and follow-up. The follow-up/baseline Sf/Am ratio was significantly associated with the LVEF ratio (r = 0.469, P = 0.037). The Sf/Am was significantly correlated with the LVEF in overall measurements (n = 40, r = 0.491, P = 0.001). These results demonstrated that a novel noninvasive pulse waveform index, the Sf/Am measured by multisensor-ABPM is associated with LVEF. The Sf/Am may be useful for estimating cardiac function.
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Narita et al. (2023) conducted an observational in Heart failure (n=20). Multisensor-ambulatory blood pressure monitoring (ABPM) measuring Sf/Am ratio was evaluated on Correlation between the pulse waveform index Sf/Am and echocardiographic LVEF (r = 0.491, p=0.001). The novel pulse waveform index Sf/Am measured by multisensor-ABPM was significantly correlated with left ventricular ejection fraction in heart failure patients (r = 0.491, P = 0.001).
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