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March 6, 1920Journal of the American Medical Association520 citationsOpen Access

Squamous-Cell Epithelioma of the Lip

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ABAlbert C. Broders

Key Points

  • This research aims to explore the differences in malignancy among squamous-cell epithelioma of the lip and understand cancer resistance.
  • Reviewed cases of lip epithelioma to assess levels of malignancy and outcomes.
  • Examined the role of defense cells in combating cancer cells, particularly focusing on fibrous connective tissue cells.
  • Identified that some lip cancers are fatal while others are not, indicating different malignancy levels.
  • Noted the significant role of defense cells, especially fibrous connective tissue cells, in inhibiting cancer cell growth.

Abstract

Of all the malignant neoplasms with which man is afflicted, few cause more concern and inconvenience than that of epithelioma of the lip. In the past, pathologists have been content to classify cancer of the lip as cancer, without any distinction as to the degree of malignancy. It is a well established fact that some cancers of the lip are fatal to patients and others are not. There must be a reason for this. One theory is that some persons are resistant to cancer, and this seems to be borne out in a certain percentage of cases. Undoubtedly, a large proportion of cancer cells are destroyed by the defense cells of the body; of these, the fibrous connective tissue cell is the most important, since it cuts off nourishment from the cancer cells. The endothelial leukocyte and lymphocyte evidently also play ah important role in the destruction of cancer cells,

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Cite This Study

Albert C. Broders (1920) studied this question.

synapsesocial.com/papers/6a0db4facae7912d2fa5398ehttps://doi.org/10.1001/jama.1920.02620100016007
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