Key result
Vegetation diameter >10 mm linked to a ~146% higher incidence of embolic events.
Why the study?
Does vegetation size determined by echocardiography predict disease-associated complications in patients with active infective endocarditis?
Observational (n=105)
Does vegetation size determined by echocardiography predict disease-associated complications in patients with active infective endocarditis?
Absolute Event Rate: 46.8% vs 19%
p-value: p=<0.01
A vegetation diameter greater than 10 mm on echocardiography identifies patients with infective endocarditis at significantly higher risk for embolic events.
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Vegetation size may refine risk stratification in infective endocarditis; leaves open whether routine transesophageal echocardiography improves outcomes.
Mügge et al. (1989) conducted an observational in Active infective endocarditis (n=105). Vegetation diameter > 10 mm vs. Vegetation diameter ≤ 10 mm was evaluated on Embolic events (p=<0.01). Patients with a vegetation diameter >10 mm had a significantly higher incidence of embolic events compared to those with a diameter ≤10 mm (46.8% vs 19.0%; p<0.01).
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