Answers are grounded in this paper and cite their sources.
Summary: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications. Availability: RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a Contact: miledywgonzalez@gmail.com; pearson@virginia.edu
No takes yet. Share an insight, caveat, or question.
Gonzalez et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: