April 1, 1989Annual Review of Immunology
The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response
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Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
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Cite This Study
Beutler et al. (1989) studied this question.