Key result
A total intravenous anesthetic regimen incorporating dexmedetomidine did not significantly interfere with sensory or motor evoked potentials during scoliosis surgery in 18 cases.
Why the study?
Does a total intravenous anesthetic regimen including dexmedetomidine allow for successful intraoperative neurophysiological monitoring during scoliosis surgery?
Observational (n=18)
Does a total intravenous anesthetic regimen including dexmedetomidine allow for successful intraoperative neurophysiological monitoring during scoliosis surgery?
A total intravenous anesthetic regimen incorporating dexmedetomidine is feasible and does not significantly interfere with intraoperative neurophysiological monitoring during scoliosis surgery.
May support TIVA with dexmedetomidine for IONM in scoliosis surgery; leaves open confirmation in larger prospective trials.
Intraoperative neurophysiological monitoring (IONM) during corrective spinal surgery is widely used. Because of the possible interference with the recording of evoked potentials by inhalational anesthetics, total intravenous anesthetic (TIVA) regimens have been advocated. TIVA regimens may be difficult to use in pediatric populations due to metabolic factors. We report on the results of multimodality IONM during 18 cases in which a TIVA regimen incorporating dexmedetomidine (Precedex, Hespira, Lake Forest, IL) was used. Monitoring techniques included sensory (SSEP) and motor evoked potentials (MEP), as well as pedicle screw stimulation. SSEPs were maintained within an acceptable range of baseline amplitude (50%) and latency (10%), and MEPs remained elicitable throughout each case. We therefore found that the anesthetic regimen did not significantly interfere with any of the monitoring modalities used and conclude that IONM in the presence of dexmedetomidine is feasible under appropriate conditions.
No takes yet. Share an insight, caveat, or question.
Anschel et al. (2008) conducted an observational in Scoliosis (n=18). Total intravenous anesthetic (TIVA) regimen incorporating dexmedetomidine was evaluated on Maintenance of sensory and motor evoked potentials. A total intravenous anesthetic regimen incorporating dexmedetomidine did not significantly interfere with sensory or motor evoked potentials during scoliosis surgery in 18 cases.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: