Physiologic determinants of the electrocardiographic diagnosis of left ventricular hypertrophy.
Key result
The product of left ventricular free wall thickness and semiminor radius (h * R) defined electrocardiographic LVH, with all patients having LVH on ECG showing h * R > 2.6 cm2.
Why the study?
What are the physiologic and geometric determinants of the electrocardiographic diagnosis of left ventricular hypertrophy?
Population
93 patients (36 with no LVH on ECG, 10 with borderline voltage for LVH, and 47 with LVH on ECG)
Design
Cross-sectional
Authors
Discussion
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Implication
h*R threshold supports ECG LVH geometry; hypothesis-generating without altering current diagnostics.
Study Design
Type
Cross-Sectional (n=93)
Structured PICO
What are the physiologic and geometric determinants of the electrocardiographic diagnosis of left ventricular hypertrophy?
P
Population
93 patients (36 with no LVH on ECG, 10 with borderline voltage for LVH, and 47 with LVH on ECG)
I
Intervention
Left ventricular (LV) cineangiograms to assess LV end-diastolic volume, free wall thickness (h), semiminor radius (R), LV mass index (LVMI), and geometric relations
O
Outcome
Physiologic and geometric determinants of left ventricular hypertrophy (LVH) inscription on the ECGsurrogate
A critical geometric relationship involving both wall thickness and chamber dilatation (h*R > 2.6 cm2) is necessary for left ventricular hypertrophy to appear on the ECG.
Cite This Study
Antman et al. (1979) conducted a cross-sectional in Left ventricular hypertrophy (n=93). Left ventricular geometry and mass parameters was evaluated on Electrocardiographic diagnosis of left ventricular hypertrophy. The product of left ventricular free wall thickness and semiminor radius (h * R) defined electrocardiographic LVH, with all patients having LVH on ECG showing h * R > 2.6 cm2.