Key result
Patients with severe calcific aortic stenosis had significantly higher fasting plasma total cholesterol than controls (mean difference 0.79 mmol/l, p=0.029), particularly with tricuspid valves.
Why the study?
Is severe calcific aortic valve stenosis associated with elevated fasting plasma total cholesterol?
Case-Control (n=40)
No
Is severe calcific aortic valve stenosis associated with elevated fasting plasma total cholesterol?
Effect estimate: Mean difference 0.79 mmol/l
p-value: p=0.029
Severe calcific aortic stenosis is associated with higher fasting plasma total cholesterol, particularly in patients with tricuspid aortic valves.
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May warrant lipid assessment in severe aortic stenosis; leaves open causal role and therapeutic implications.
Wilmshurst et al. (1997) conducted a case-control in Calcific aortic valve stenosis (n=40). Severe calcific aortic stenosis vs. Controls was evaluated on Fasting plasma concentrations of total cholesterol (Mean difference 0.79 mmol/l, p=0.029). Patients with severe calcific aortic stenosis had significantly higher fasting plasma total cholesterol than controls (mean difference 0.79 mmol/l, p=0.029), particularly with tricuspid valves.
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