February 13, 2008Journal of Cardiovascular Electrophysiology
Long‐Term Outcome Following Successful Pulmonary Vein Isolation: Pattern and Prediction of Very Late Recurrence
Key result
Late recurrence of atrial fibrillation occurred in 8.7% of patients who were initially AF-free for ≥1 year post-PVI, with actuarial recurrence reaching 25.5% at 5 years.
Population
264 patients who underwent pulmonary vein isolation for atrial fibrillation and demonstrated ≥1 year AF-free…
Design
Cohort
Follow-up
28 ± 12 months (range 1-5 years)
Authors
Discussion
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Implication
May warrant extended post-PVI surveillance despite 1-year success; leaves open optimal monitoring duration and reconnection prevention strategies.
Study Design
Type
Cohort (n=264)
Structured PICO
P
Population
264 patients who underwent pulmonary vein isolation (PVI) for atrial fibrillation (AF) and demonstrated ≥1 year AF-free follow-up on no antiarrhythmic drugs (from an initial series of 350 consecutive patients). Mean age 57 ± 12 years, 71% male, 87% paroxysmal AF.
I
Intervention
Pulmonary vein isolation (PVI) ablation
O
Outcome
Late recurrence of atrial fibrillation (after ≥1 year AF-free period)hard clinical
Despite an initial 1-year AF-free period after PVI, late recurrence occurs in up to 25.5% of patients at 5 years, is strongly associated with pulmonary vein reconnection, and is predicted by hypertension and hyperlipidemia.
Cite This Study
Shah et al. (2008) conducted a cohort in Atrial fibrillation (n=264). Pulmonary vein isolation (PVI) was evaluated on Late recurrence of AF. Late recurrence of atrial fibrillation occurred in 8.7% of patients who were initially AF-free for ≥1 year post-PVI, with actuarial recurrence reaching 25.5% at 5 years.