Key result
DOACs and warfarin show similar LAA thrombus rates in patients with NVAF.
Why the study?
Does DOAC compared to warfarin reduce the prevalence of LAA thrombi in Japanese NVAF patients undergoing preprocedural TEE?
Population
Japanese non-valvular atrial fibrillation patients undergoing preprocedural transesophageal echocardiography…
Comparison
Direct oral anticoagulants (DOAC) vs Warfarin
Design
Cohort
Authors
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Similar LAA thrombus rates do not guide anticoagulation choice; leaves open randomized TEE confirmation in Japanese NVAF.
Observational
Does DOAC compared to warfarin reduce the prevalence of LAA thrombi in Japanese NVAF patients undergoing preprocedural TEE?
LAA thrombi are present in 2.7% of Japanese NVAF patients on anticoagulation prior to procedures, with similar rates between DOACs and warfarin.
Kawabata et al. (2017) conducted an observational in Non-valvular atrial fibrillation. Direct oral anticoagulants (DOAC) vs. Warfarin was evaluated on Prevalence of left atrial appendage (LAA) thrombi. Direct oral anticoagulants and warfarin showed a similar incidence of left atrial appendage thrombi (overall prevalence 2.7%) in Japanese patients with non-valvular atrial fibrillation.
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