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December 1, 1985Histopathology

The assessment of cardiac hypertrophy at autopsy

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Why the study?

Does the Fulton technique provide a more accurate assessment of cardiac hypertrophy at autopsy compared to ventricular wall thickness or total heart weight?

Population

Normal adult human hearts at autopsy

Comparison

Fulton technique for isolated ventricular weights vs Ventricular wall thickness and total heart weight

Design

Review

Authors

JHJ R HangartnerSt George's, University of LondonNMN. J. E. MarleySt Bartholomew's HospitalAWAnna WhiteheadWestern Health

Discussion

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Implication

Supports prioritizing Fulton technique with body weight references in autopsy hypertrophy assessment; leaves open validation of non-arbitrary criteria.

Structured PICO

Does the Fulton technique provide a more accurate assessment of cardiac hypertrophy at autopsy compared to ventricular wall thickness or total heart weight?

P
Population
Normal adult human hearts at autopsy
I
Intervention
Fulton technique for isolated ventricular weights
C
Comparator
Ventricular wall thickness and total heart weight
O
Outcome
Determination of the presence or absence of ventricular hypertrophysurrogate

The Fulton technique for isolated ventricular weights is the most reliable method for assessing cardiac hypertrophy at autopsy, whereas ventricular wall thickness is insensitive.

Limitations

  • Use of arbitrary upper and lower limits for isolated ventricular weights obtained by Fulton's method may lead to errors

Cite This Study

Hangartner et al. (1985) studied this question.

synapsesocial.com/papers/6a0e4dfabc348c84f2fd99dehttps://doi.org/10.1111/j.1365-2559.1985.tb02811.x
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Hypertrophy in Patients with Chronic Bronchitis and Emphysema1974 · 76 citations
  2. 2Recent Advances in Clinical Pathology1947 · 48 citations